Honokiol Formula

Honokiol Formula

Pure Honokiol—Nature’s “Smart Drug”

Pure honokiol is a highly active compound extracted from Magnolia officinalis bark. Thousands of published studies and extensive clinical use show pure honokiol delivers a remarkable array of powerful therapeutic actions.

  • Fights cancer through multiple mechanisms
  • GABA enhancer: promotes relaxation and sense of calm
  • Protects neurological and cognitive health
  • Powerful antioxidant
  • Anti-inflammatory
  • Antimicrobial
  • Supports restful sleep
  • other benefits

Because of its broad-spectrum of benefits and excellent safety profile, pure honokiol has become an essential strategy for protecting and enhancing numerous key areas of health.

Multiple Mechanisms of Action

It’s rare that one single ingredient can exert so many powerful actions. Pure honokiol is one of these unique compounds. It supports the treatment and prevention of numerous health conditions, targeting a diverse range of pathways with potent bioactivity.

  • Anti-cancer: Extensive published research shows pure honokiol works on critical cell signaling and genetic pathways to halt cancer growth, promote apoptosis in cancer cells, and disable the metastatic process. It is also shown to enhance certain conventional cancer protocols —including synergy with chemotherapy and radiation— and prevent multi-drug resistance.
  • Powerful neurological support: Pure honokiol has the unique ability to cross the blood-brain and blood-cerebral-spinal fluid barriers, delivering powerful protection and support for neurological health. Research shows it promotes the growth of healthy nerve cells, inhibits neuro-inflammation, and addresses amyloid plaque build up in the brain associated with Alzhimer’s. Pure honokiol is also shown to support against other neurological conditions such as Parkinson’s.
  • Relaxation and mood support: Pure honokiol enhances the activity of GABA, a primary neurotransmitter associated with relaxation and a sense of calm. Pure honokiol is a powerful way to help relieve stress and anxiety, and support deep, restful sleep.
  • Antioxidant activity: As an antioxidant, pure honokiol is 1,000 times more potent than Vitamin E in scavenging free radicals and addressing oxidative stress.
  • Mitochondrial support: Mitochondria are the tiny cellular engines that produce energy for the body. Mitochondrial health is essential for preventing chronic disease and ensuring healthy aging. Honokiol supports mitochondrial activity by enhancing the actions of SIRT1, a key protein essential for healthy mitochondrial function.
  • Anti-microbial: Pure honokiol is active against a number of aggressive microbes including bacteria, fungi, viruses and parasites, offering critical support in treating a wide range of infections.

Purity Matters

When it comes to honokiol’s efficacy, purity matters. Research continues to show that the important benefits of honokiol are achieved with a purified extract, vs. a lower-grade combination of honokiol and other compounds.

Because of the broad spectrum of critical benefits, pure honokiol has become a trusted ally in integrative medicine, alongside clinically researched Modified Citrus Pectin and other advanced therapies earning their place as some of the most powerful natural natural solutions for long-term health and vitality.


Select Honokiol Research Links:

2019 study: Honokiol Attenuates Memory Impairments, Oxidative Stress, Neuroinflammation in Vascular Dementia

2019 study: Antidepressant-Like Effect and Mechanism of Action of Honokiol

2019 study: Honokiol Improves Insulin Resistance, Hepatic Steatosis, and Inflammation in Type 2 Diabetes

2018 study: Honokiol Alleviates Cognitive Deficits of Alzheimer’s Disease by Activating Mitochondrial SIRT3.

2018 study: Honokiol: An Anti-Cancer Lignan

2017 Review: Neuroprotective effects of honokiol: from chemistry to medicine.

2016 study: Honokiol, an Active Compound of Magnolia Plant, Inhibits Growth, and Progression of Cancers of Different Organs

View additional Honokiol research abstracts in our Research Library: