New Study Shows How Modified Citrus Pectin Fights Breast Cancer

Research on the super-nutrient modified citrus pectin (MCP) continues to gain momentum—showing just how remarkable this single natural ingredient is.

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Research on the super-nutrient modified citrus pectin (MCP) continues to gain momentum—showing just how remarkable this single natural ingredient is.

From halting and even reversing cancer, heart and kidney disease, and other degenerative conditions, to gently removing toxins and much more, there’s a reason why more and more researchers are rushing to study the original form of opens in a new windowmodified citrus pectin.

One recent animal study on MCP adds to this growing body of data, showing us again how it works to inhibit cancer growth and metastasis.1

What’s interesting about this recent study is that it shines new light into some of cancer’s mechanisms, and how the only researched form of MCP works to stop them.

Before we dive into this new information, though, let’s take a look at what makes MCP so unique and effective against cancer, and so many other life-threatening conditions.

The Only Available Galectin-3 Blocker

The researched form of MCP is known as the only available ingredient to block a protein in the body called galectin-3 (Gal-3). This protein is naturally occurring and acts as a “survival protein” because it’s activated in response to injury, illness, stress, and other threats. Gal-3 triggers your body’s repair and survival mechanisms, including inflammation—which is helpful in small amounts.

The problem is though, Gal-3 often doesn’t turn off when the threats—whether perceived or real—have passed. With our fast-paced lifestyles, increasing exposure to toxins, and ongoing stress, the body keeps producing Gal-3—sending out inflammatory survival signals like an alarm that won’t turn off.

Thousands of studies show how this harmful Gal-3 activity leads to chronic inflammation, fibrosis (uncontrolled scar tissue build-up) of organs and tissues, tumor formation and metastasis, immune imbalances, and much more. Gal-3 has even been called, “The Guardian of the Tumor Microenvironment” because it helps cancer grow while shielding it from your immune system.

In a profound paradox, when this survival protein Gal-3 is out of control, it becomes a key driver of our most deadly and debilitating conditions, from heart disease and kidney failure, to the infamous cytokine storm that’s especially concerning in aggressive infections.

From this extensive body of research on Gal-3, one agent has emerged as a safe and effective way to block and reverse the damage: The researched form of modified citrus pectin.

The ability of this MCP to halt—and in many cases even reverse—the impacts of Gal-3 make it a central cornerstone not only in the prevention and treatment of metastatic cancer, but numerous other inflammatory conditions now found to be driven by unhealthy expression of Gal-3. 

New Study: How Gal-3 Fuels Breast Cancer — And How MCP Stops It

The new study on the role of MCP and Gal-3 in opens in a new windowbreast cancer adds to this growing body of data. Published in June in the journal, Biochemical Pharmacology, this research sheds new light on the mechanisms that promote unhealthy levels of Gal-3 in the tumor microenvironment—and how MCP helps.  

In this study, researchers looked closely at a group of immune cells that are found in high numbers around tumors. These specific immune cells are called Tumor-associated macrophages, and they’re usually associated with a poor outcome in cancer. They’re also primarily found in the hypoxic regions of a tumor microenvironment—the areas around the tumor where tissues are not getting enough oxygen.

What’s interesting is that this new study showed for the first time that hypoxia—lack of oxygen in the cells and tissues—increases the production of Gal-3. This increase in Gal-3 directly fuels tumor growth and metastasis through multiple mechanisms. 

Stress, Galectin-3 and Disease

Hypoxia is what happens when cells can’t get oxygen. In the same way, when we’re struggling and stressed, we often feel as though we can’t take a deep breath. It’s an example of how stress-fueled “survival mode”—which we’ve all experienced—produces chemicals in our bodies that can dramatically hinder long-term health.

But by blocking Gal-3, and using other methods to calm our stress response, we can help stop and even reverse these damaging impacts.

The results of this new breast cancer study showed that MCP worked to block Gal-3, and in doing so, inhibit tumor growth and metastasis in an animal model of breast cancer.

The data also showed that when MCP was combined with a drug that helps stop angiogenesis (new blood vessel growth to tumors), the anticancer benefits were more significant than using either agent alone. This synergistic effect adds to the research showing the remarkable ability of MCP to enhance the benefits of other therapies—from chemotherapy drugs and antibiotics to herbal formulas and even clinical treatments. 

Controlling Galectin-3: The Key to Long-Term Health

The data is in. Extensive published research and clinical observations show that controlling Gal-3 can slow, stop, reverse, and prevent the progression of our most serious and debilitating diseases. But to do this, you need an effective Gal-3 blocker: The original and researched form of modified citrus pectin. 

By binding and blocking the Gal-3 signals that wreak havoc throughout your body, this form of  MCP is becoming known as one of the most important daily strategies for safeguarding your long-term health and vitality.


1. Wang L, Li YS, Yu LG, et al. Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression. Biochem Pharmacol. 2020;178:114113.

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